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basic sciences and the fields of clinical and social sciences related to health, to promote knowledge about neurodegenerative dementias and its application. A team of specialists in Neurology, Psychiatry and Neuropsychology, together with the participation of geriatricians, occupational therapists, physiotherapists and social workers from the Center’s healthcare area make up this part of the Unit. The evaluations carried out in these areas composed the clinical and sociological da- tabase that, in addition to its intrinsic interest for research purposes, supports the biological samples and neuroimaging data obtained systematically in the Center.
In addition to the clinical departments, the UIPA has a translational perspective in its original project, made up of the departments of Biochemistry and Molecular Genetics, Neuropathology and Neuroimaging. These three areas bring together the most promising fields of research on the biological processes underlying de- mentia.
The UIPA is characterized by its marked multidisciplinary approach, so that both clinical and basic aspects are in continuous contact, through those five depart- mental areas, elaborating and contrasting hypotheses, and jointly carrying out various research projects. On the other hand, it is from reinforcing these two per- spectives, how concepts such as translational research in Medicine have been developed. The scientific activity of the CIEN Foundation is based on this idea: to transfer to the clinical field the advances obtained with basic research.
3.2.1. Department of Neurology
Neurology as a medical-scientific discipline aims to study the structure and func- tion of the nervous system, the identification, description and analysis of its nu- merous and varied pathologies, the diagnosis of its clinical alterations and the treatment of patients who suffer them. In the field of cognitive impairment, the neurologist must characterize the numerous types and variants of this syndrome through a systematic clinical evaluation of the patient and his/her environment, collaborate with other specialists in psychology, radiology, laboratory, genetics, neurophysiology, etc. make a diagnosis and prescribe and monitor a treatment. In a research group such as the Queen Sofia Foundation Alzheimer Center (CAFRS, for its acronym in Spanish), the Neurology team offers basic clinical support to all studies carried out with volunteers and patients, generates and implements clinical research hypotheses and collaborates with the other teams of specialists in clinical and basic research, in the early detection, prevention and treatment of Alzheimer’s disease and other related pathologies. The Department of Neurology develops the following activities:
• General and neurological medical evaluation, and clinical diagnosis of the Vall- ecas Project participants
• Detection and management of possible clinical complications of the Vallecas Project participants.
• Preparation of clinical reports
• Evaluation and diagnosis of patients attending the Center
3. Scientific activity
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