Page 44 - MaquetaFundCIEN-2019-ENG

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Annual Report 2019
• Neurological monitoring of patients admitted to the Residence
• Management and curation of databases.
• Statistical analysis and preparation of scientific reports.
• Teaching and mentoring of graduate and PhD students who collaborate in some
research projects
• Communication in scientific forums of research work carried out in the depart-
ment.
• Development of research projects on neurodegenerative diseases, especially fo-
cused on Alzheimer’s disease.
• Dissemination to society of the progress of the investigation.
Main lines of research
The activities of this department focus on the following main areas:
1. The Vallecas Project cohort: (due to its size, a complete section in this report is dedicated to this study, see section 4 of this Report). In this project, it is carried out an annual systematic clinical and neurological evaluation of the more than one thousand volunteers participating in the study cohort. This information, together with the data from the neuropsychological assessment, allows establishing the evolutionary diagnosis of each subject and is stored in a large database for carry- ing out various research projects.
2. Queen Sofia Foundation Alzheimer Center Research Program (CAFRS) cohort:
it consists on the systematic clinical evaluation, every six months, of the patients who are in the CAFRS, both in internment regime (Units of Life) and in day care (Day Center). This evaluation, carried out together with the rest of the staff from the Center and healthcare professionals leads to the syndromic and etiological diagnosis and to the protocoled collection of neurological, psychiatric, neuropsy- chological, demographic, analytical, therapeutic and neuroimaging data. This sys- tematic gathering of information, from the moment the patient enters the study until it is transferred to another Day Center or passes away, allows for the genera- tion of a large database of clinical data that can be exploited in itself or in relation to the neuroimaging and/or neuropathological data.
In 2019, there were 16 new admissions in the Day Care Center and in the Resi- dence, all of them signed the consent to participate in the multidisciplinary peri- odic evaluations. On top of the baseline evaluations, a total of 973 clinical evalu- ations (semi-annual frequency), 32 brain MRI studies (annual frequency) and 210 analytical studies were carry out.
3. Other ongoing research projects: The Department of Neurology, with its own resources or, more often than not, in collaboration with other CAFRS or external groups, is carrying out several other research projects. Most of them are mainly based on information o from the Vallecas Project or the Queen Sofia Foundation Alzheimer Center Research Program databases. In other instances, information provided by various collaborators is used.