Page 40 - Memora anual Fundación CIEN 2015

neuropsychological evaluation to know the thods that meet all these needs. Information from 20
clinical and cognitive profile of the
participants.
- After signing informed consent, sampling of
tears (Schirmer technique) in participants
(individuals with no cognitive impairment,
patients with mild cognitive impairment and
patients diagnosed with mild Alzheimer
disease - Reisberg stages GDS 3 and 4).
- Determination in the laboratory of the
biomarkers.
- Comparison of the results from the three study
groups.
- And developing a database to harbor all
associated patient information / controls and
samples.
All this in order to find biomarkers related to AD that patients it was included the performance by the re-
allow us to make the diagnosis of the disease and to
elucidate its evolution and prognosis.
Recruitments of participants begun in 2014 and finis-
hed during 2015. It involves the Association of Rela-
tives of Alzheimer's patients and other dementias at
Soria, Leon Alzheimer's Association, CIEN Foundation
and Center of Molecular Biology Severo Ochoa.
About 100 samples have been collected in total,
which will be analyzed at the Center for Molecular
Biology Severo Ochoa throughout 2016.
Among the activities in the area
of Neuropsychiatry of UMA are included
the following:
IDEAL Scale
Participation in "VaIidation of the IDEAL Scale in Spa- information is collected on the following tests: Neu-
nish population: a multicenter study in patients with
dementia." The study attempts to validate in Spain a
scale that values multiple dimensions of dementia.
The aim is to better detect the different needs of
care for patients with dementia. It is known that dif-
ferent patients with dementia have different needs,
but there are currently no adequate screening me-
CIEN Foundation Annual Report 2015 / 40
patients attending the Alzheimer Day Centre Foun-
dation Reina Sofia Center (CAFRS) with their infor-
med consent available has been gathered for this
study. Clinical information was obtained both
through interviews with family members as well as
with the application of different existing validated
scales that assess behavioral and psychological
symptoms of dementia (BPSD), caregiver burden,
functionality and overall cognition.
Personality in dementia
This research line attempts to relate the previous per-
sonality of the patient with the development of dif-
ferent BPSD or other cognitive symptoms in
dementia. For years, during the initial evaluation of
ference family of the NEO-FFI inventory. This year the
Hetero-anamnesis Questionnaire of Personality (PAH,
in its original Dutch version) has been included after
its translation to Spanish. The goals of this research
are the validation of this scale in Spain, its compari-
son with the results obtained in the inventory NEO-FFI
and its correlation with clinical data of the patients
under study.
Longitudinal study of CAFRS patients
It consists of gathering information every other year
from all patients at Day Care Centre and the Resi-
dence who have provided consent to perform the
evaluation tests. There is a longer yearly assessment
held in the first half of the year, and a shorter assess-
ment in the second half. In patients from Residence
information is gathered through the reports of the
coordinators of the CAFRS Life Units. In the semester
ropsychiatry Inventory (NPI), Cornell Scale for De-
pression in Dementia, Cohen-Mansfield Agitation
Scale in Dementia (CMAI), Apathy Inventory (IA),
and NH APADEM Apathy Scale. In the second se-