Page 79 - Memora anual Fundación CIEN 2015

4. VALLECAS PROJECT

determine the volume reduction of the puting and Visualization Center of Madrid), a center
amygdala, hippocampus, entorhinal cortex, from the UPM (Technical University of Madrid) has
etc. also been established.

• Diffusion Study (b: 800) As a result, a VBM analysis of T1 sequences from visits
White matter, partly due to Wallerian 1 and 2 of the subjects 'Vallecas Project' has been
degeneration and partly to reduced performed. The results of this analysis have been
connectivity by decreased cortical activity, used to present a paper at the last meeting of the
presents ultrastructural changes that can be 'Society for Neuroscience (Neuroscience 2015 “MRI
detected with diffusion techniques (DTI). in the healthy elderly predicts subsequent develop-
ment of mild cognitive impairment", Chicago, 17 to
• Brain Perfusion Study
Cerebral perfusion related to cortical activity Vallecas Project
may be assessed -without needing to inject activities during 2015
contrast-through MR sequences (Arterial Spin
Labelling, ASL) and therefore hypofunctioning
areas will present decreased perfusion.

Throughout 2015 all Neuroradiology reports from Number of second visit assessments 24
every subject and each of the visits from the 'Valle- Number of third visit assessments 258
cas Project' have been incorporated in the single Number of fourth visit assessments 469
project database. Text reports have been encoded, Number of fiŌh visit assessments
incorporating each item to the database, as well as 6
attaching the report of each visit in pdf format, en-
abling viewing and downloading to all researchers
who have access to the database.

On the other hand, we have organized MRI data co- Second visit
rresponding to the 'Vallecas Project' and Queen Third visit
Sofia Foundation Alzheimer Center subjects, con- Fourth visit
verting the data obtained directly from MRI equip- Fifth visit
ment into the appropriate format for analysis.
A collaborative project with CESVIMA (Supercom-

NEUROIMAGING ACQUISITIONS 1% 3%

Second visit 18 62% 34%
Third visit 224
Fourth visit 377
Fifth visit
Total 6
625

CIEN Foundation Annual Report 2015 / 81