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21 October 2015). the first two visits have been designed to assess three
different but complementary aspects. First, we stu-
4.3.9. Current State died the possible correlation between the informa-
tion obtained from medical records (gender, age,
The Vallecas Project is the main research project medication, past illnesses, ApoE genotype, etc.) of
conducted at CIEN Foundation, both in terms of re- the volunteers with the appearance or not of mild
sources and social impact. In late 2013, the project cognitive impairment (MCI). Secondly, we have also
completed the recruitment phase and the baseline examined the possible association between cogni-
first visits of volunteers. During 2015, we have combi- tive complaints expressed by the volunteers on the
ned the second, third, fourth and fifth visits from vo- first visit and its role as an early marker of progression
lunteers, already surpassing study's half point. to MCI a year later. Finally, we have carried out a
comparative study of magnetic resonance imaging
The following table shows the status of clinical eva- of the volunteers who have transitioned from a cog-
luations conducted to date. nitively healthy status to show signs of MCI in the se-
cond visit of 'Vallecas Project'. The purpose of this
In order to ensure the reliability of the data collec- study was to try to identify changes in brain structure
ted so far in the context of the Vallecas Project, that can be determined by neuroimaging techni-
throughout 2015 we have continued with the vali- ques. Some of these results have been submitted
dation process of all information registered by the and are pending publication in scientific journals.
various departments. The first analysis of data from In addition to continuing with ongoing studies, new
VALLECAS PROJECT CLINICAL EVALUATIONS (OCTOBER 2011-DECEMBER 2015)
First visit 1.175
Excluded at baseline 47
Second visit 966
Third visit 836
Fourth visit 484
Fifth visit 6
Drop outs 395
Do not comply with inclusion criteria 30
Deceased 17
Diagnosis of neurological disease 31
Volunteer withdrawal 317
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