Page 85 - MaquetaFundCIEN-2019-ENG

4. The Vallecas Project
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VISITAS
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Cognitive performance
Reading test to evaluate premorbid intelligence
Mini Mental State Examination (MMSE)
Clock Drawing Test
Free And Cued Selective Reminding Test (FCSRT)
Semantic Lexical Evocation (P, M, R)
Semantic Verbal Fluency (Animals, Fruits and Vegetables, Kitchen Utensils)
Number Key (WAIS-III)
Rey-Osterreith Complex Figure Test
Forward and reverse digits (WAIS-III)
Symbolic gesture and Imitation of bilateral postures (TBR)
Rules Change (BADS)
Test of the five points
Boston Naming Test (BNT-15)
Cognitive complaints
Interview for the assessment of cognitive complaints
Memory Failures in Everyday (MFE)
Depression and anxiety
Geriatric Depression Scale (GDS-15)
State-Trait Anxiety Inventory (STAI)
Functional scales
Functional Activities Questionnaire (FAQ)
4.3.6. Determination of biomarkers
It is currently widely accepted that the molecular changes associated with AD, including the formation of amyloid plaques and neurofibrillary tangles begin many years before the appearance of clinical symptoms. In recent years, the need to define and develop new early biomarkers of AD that allow us to assess the risk and early diagnosis of the disease has become clear. Thus, blood sam-