Page 63 - Annual Report 2018

3. SCIENTIFIC ACTIVITY

carry out a complementary and synergistic appro- lecular, clinical, or neuroimaging signals that may
ach to evaluate, validate and standardize the iden- serve to define populations at higher risk of develo-
tification, monitoring, quantification and functional ping dementia in the future.
validation of miRNAs in plasma samples taken from
elderly subjects who are cognitively normal, show Dementia Genetics Spanish Consortium (DEGESCO)
deterioration cognitive mild or moderate dementia,
in the presence or absence of peripheral vascular Also, during this year, the CIEN Foundation has con-
pathology. Following a multidisciplinary approach, tinued participating in Dementia Genetics Spanish
the analysis of the data obtained will benefit from Consortium (DEGESCO) in which a number of Spa-
the availability of other data generated within the nish research groups share genetic data within this
Vallecas project (sociodemographic data, clinical consortium to achieve greater study power in de-
history, annual neurological evaluation, neurops- mentia genetics and especially in the Alzheimer's di-
ychological evaluation, structural and functional sease. In the context of DEGESCO, during 2018,
brain MRI, genotyping, etc.) in order to identify mo- research activities continued to be carried out orien-

Samples obtained up to December 31, 2018
according to the number of semiannual evaluations

333
Residence Day Care Center
296

262

Samples (n) 216 191 162 148

132 135 130 120
97
90
80
75 69 65
58 44
35 38 33
26 26
13 9 5 4 4 4 2 1 1 0 0 0 18 0 14 0 8 0 2 0
1st 2nd 3rd 4th 5th 6th 7th 8th 9th 10th 11th 12th 13th 14th 15th 16th 17th 18th 19th 20th 21th 22th
Evaluation

CIEN Foundation Annual Report 2018 / 63