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2.1. Overview


            On January 18, 2006, the CIEN Foun-
            dation signed an agreement with
            the Queen Sofia Foundation, under
            which the former assumes the ma-
            nagement of the Alzheimer Project
            Research Unit (UIPA, for its acronym
            in Spanish). The context in which
            the UIPA is framed is the Alzhei-
            mer Project, promoted by the
            Queen Sofia Foundation. The
            main exponent of this project is
            the Queen Sofia Foundation Al-
            zheimer Center (Alzheimer Com-
            plex), located in the Vallecas nei-
            ghborhood (Madrid), which in 2017
            has celebrated its 10th Anniversary.
            One of the most outstanding as-
            pects of the Alzheimer Complex is
            that there is a Healthcare Center (for-
            med by a Residence and a Day Center)
            for Alzheimer's patients and related
            diseases as well as a Training Center, in       focus in Alzheimer's disea-
            addition to the UIPA. This Unit began           se and related dementias.
            its activity in April 2007, while the heal-
            thcare activity began at full capacity in       Through this series of studies, new
            the second half of that year.                   knowledge in genetics and molecular
                                                            biology that have different applications
            Currently, the UIPA consists of five            is generated, that teach the resear-
            departments with a clear multidiscipli-         chers about the pathogenic mechanis-
            nary approach and with specific objec-          ms of the disease which can be in turn
            tives, among which are the following:           implemented into the field of diag-
            the monitoring and periodic evaluation          nosis and, desirably, can result in the
            of patients at the Alzheimer Center; the        development of better treatments.
            development of clinical, epidemiologi-
            cal, genetic, research projects as well         However, far from promising a simple
            as on biomarkers in biological samples          solution to the problem of neurodege-
            or neuroimaging, in the field of neuro-         nerative dementias, these advances
            degenerative diseases, with special             anticipate an increasingly complex





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