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PI: Dr. Stephan Moratti, Basic                  Episodes: Randomized, Double-
                      Pasuchology I Professor.                        Blind, Placebo-Controlled Clinical

                   •  PURPOSE “Placebo-controlled                     Trial" (Exp/n. SAM18PI02/2019). Dr.
                      trial in subjects at ultra-high Risk            Celso Arango López. Child and
                      for Psychosis with Omega-3 fatty                Adolescent Psychiatry Service,
                      acids in Europe”. PI: Dr. Covadonga             Department of Psychiatry. Gregorio
                      Martínez Díaz-Caneja.                           Marañón University General
                                                                      Hospital.
                   •  "NAC II": "Combination of N-Acetyl
                      Cysteine (NAC) Treatment and                 •  “Study of the
                      Cognitive Training to Promote                   Ethiophysiopathological
                      Changes in Behavioral and Neural                Mechanisms Involved in the
                      Activation Patterns Underlying                  Progressive Loss of Brain
                      Cognitive Deficit in Adolescent                 Gray Matter in Children and
                      Psychosis" (Exp/n. FAK182018). Dr.              Adolescents with a First Psychotic
                      Marta Rapado Castro. Child and                  Episode, Adolescents at Risk and
                      Adolescent Psychiatry Service,                  Healthy Controls by the Alonso
                      Gregorio Marañón University                     Family Foundation” (Exp/nº
                      General Hospital, Faculty of                    FIBHGM_CCA004-2018). PI: Dra.
                      Medicine, Complutense University,               Marta Rapado Castro. Child and
                      CIBERSAM                                        Adolescent Psychiatry Service,
                                                                      Gregorio Marañón General
                   •  "Effect of 48-Week                              University Hospital, Faculty of
                      N-Acetylcysteine Treatment                      Medicine, Complutense University,
                      on Gray Substance Loss and                      CIBERSAM.
                      Oxidative Metabolism in Patients
                      with Early-Onset First Psychotic             •  “Observational study in young
                                                                      people with high-risk mental
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