Page 107 - Libro Memoria Cien Inglés
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4.3.3. Clinical evaluation                          of physical activity and sleep
                                                                      for a week. During that period,
                  At each visit relevant information is               the following records have been
                  collected from each volunteer by appl-              registered
                  ying a semi-structured clinical inter-
                  view:                                                  »  2017: 251 records

                   •  Vascular risk factors: blood                       »  2018: 375 records
                      pressure, diabetes mellitus,                       »  2019: 181 records
                      smoking, heart disease, stroke
                                                                  Distributed as follows:
                   •  Neurological history: mental
                      retardation, head injuries, etc.                   »  Volunteers with only 1 record: 249
                   •  Consumption and/or toxic                           »  Volunteers with 2 records: 262
                      addiction: alcoholism/level of                     »  Volunteers with 3 records: 12
                      regular alcohol intake, addiction/
                      consumption of other psychotropic           Hence, we have a sample size of 523
                      substances.                                 volunteers with at least one record

                   •  Psychiatric pathology: depression,          already registered, and 274 volunteers
                      dysthymia, bipolar disorder,                with a second record after one year
                      psychotic disorders, anxiety                follow up.
                      syndromes.                                  This information must be processed

                   •  Other relevant systemic diseases:           to obtain several variables related to
                      hepatic failure, renal failure,             light, moderate or intense activity, as
                      Obstructive Sleep Apnea Syndrome            well as indicators of sleep duration and
                      (OSA)...                                    pattern.

                   •  Family history with special
                      attention to the history of
                      dementia or movement disorders,             4.3.4. General examination
                      developmental delay, or psychiatric         All subjects undergo a general and
                      disorders.
                                                                  neurological standard examination:
                   •  Regular drug treatment during the           cranial nerves, muscle balance, coordi-
                      last 5 years.                               nation, extrapyramidal system, gait, os-

                   •  From 207 to 2019, all volunteers            teotendinous reflexes, midline release
                      who consent to carry an                     reflexes, etc. The following parameters
                      accelerometer device (Actigraph®),          are analyzed in a special way:
                      similar to a wristwatch, are being           •  Gait disturbance
                      provided with it for the recording
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