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samples protocols.                                  for granting support to R+D+i
                                                                Projects "Research Challenges",
            Research Program of the Queen Sofia                 corresponding to the State
            Foundation Alzheimer Center: Syste-                 R+D+i Program aimed at Society
            matic evaluation, by means of a proto-              Challenges, within the framework
            col adapted and agreed upon, of the                 of the State Plan for Scientific
            patients institutionalized in the Queen             and Technical Research and
            Sofia Foundation Alzheimer Center                   Innovation 2017-2020. Funded by
            (CAFRS, for its acronym in Spanish)                 the Ministry of Science, Innovation
            and attendants to the Day Care Cen-                 and Universities. Project title:
            ter, after signing a proper informed                Family history of Alzheimer's
            consent. This evaluation includes the               disease in older people: influence
            following:
                                                                of subjective cognitive impairment.
                                                                Principal Investigator: Dr. Miguel
             •  Neurological evaluation
                                                                Ángel Fernández.
             •  Neuropsychological assessment                   Duration: 01/01/2019 - 16/07/2020.
             •  Psychiatric evaluation                          On February 24, 2021, the Director
                                                                of the State Research Agency signs
             •  Functional evaluation
                                                                and communicates the agreement
             •  Magnetic resonance imaging                      to start the procedure for the early
             •  Blood sampling and analysis of                  termination of the R+D+i research
                genetic risk factors                            project due to the absence of link
                                                                between the principal investigator
             •  Extraction and neuropathological                2 and the reference research pro-
                study of brains donated by                      ject RTI2018-098762-A-C32, since
                deceased patients
                                                                July 16, 2020.
            Other research projects granted in               •  PT17/0015/0014: Biobank Platform.
            competitive competition in force in                 Principal Investigator: Dr. Alberto
            2020:                                               Rábano Gutiérrez. Project funded

                                                                by Resolution of the Director of
             •  RTI2018-098762-A-C32. Call for                  the Carlos III Institute of Health, of
                projects with resolution date on                December 4, 2017, by which grants
                August 26, 2019, from the Secretary             are awarded for support research
                of State for Universities, Research,            Platforms in health sciences and
                Development and Innovation                      technologies of the 2017 call for
                and the Presidency of the State                 Strategic Action in Health, with
                Research Agency, approving                      a total budget of 135.300 euros,
                the call for early processing for               distributed in 3 annuities of 45,100
                the year 2018 of the procedure                  € each. The Carlos III Institute of






               Annual report Fundación CIEN                                                         32
               2020
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