Page 57 - Libro Memoria Cien Inglés

obtained over the years in this line of • • A pilot study has been carried
research, the following are noteworthy: out with an attentional blinking
task among the subjects of the
• Cognitive, tests and in particular, Vallecas Project. The attentional
the Free and Cued Selective blink task is a classic paradigm in
Reminding Test (FCSRT) verbal Experimental Psychology whose
episodic memory test, are the use has not been extended to
most sensitive tools for identifying clinical samples. It allows obtaining
subjects at risk of conversion to first-order cognitive parameters
MCI. Its discriminating capacity is
above other variables of interest
such as APOE genotyping.
• The predictive capacity of the
FCSRT has been shown to be
high even in a 4-year follow-up.
Especially useful is the parameter
of immediate free recall, in which
an individual's score below 18 is
considered risk for conversion in
the next 4 years.

• Processing speed (i.e., mental
agility) is another cognitive
parameter that has been revealed
as an early marker of interest for
MCI although we still need to
carry out additional analysis in this
regard.

• The analysis of the possible effect
of drugs on cognitive performance
in the Vallecas Project cohort has
been examined. The two-year
cross-sectional and longitudinal
results have not identified any
effects of interest and, when any
association has been found, it is
inseparable from the underlying
pathology of the drug itself.