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not explored in conventional                    we have incorporated into the
                evaluations that may be of interest             Vallecas Project as of the evaluation
                as early markers. Our preliminary               visit 6. The same was also done
                results show a high correlation                 with the inventory of cognitive
                between performance in the                      symptoms (MFE-11).
                attentional blink task and classical
                cognitive parameters. It is pending         The relationship between cognitive
                to investigate whether differences          reserve and socioeconomic status with
                at the fMRI level exist.                    the onset of cognitive impairment. The
                                                            cognitive reserve is a theoretical cons-
             •  Given that the experience in                truct that formulated several decades
                applying the State-Trait Anxiety            ago to explain the lack of correspon-
                Inventory (STAI) test during the            dence between the degree of brain
                Vallecas Project baseline visit raised      damage and clinical symptoms some-
                serious doubts about its suitability        times observed among patients. It is
                for our reference population, a             presumed as an individual capacity
                psychometric study was carried out          that develops throughout the life cycle
                and published to reduce test items          fundamentally through formal educa-
                and categories of response. As a            tion, the type of professional activity
                result, a much more useful reduced          performed, and the intellectual activity
                scale was obtained, but just as             developed. Numerous studies have
                precise as the original one, which          supported the protective role played









































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