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• Other projects tified some miRNAs, and developed
advanced techniques for determining
Currently, several lines of study are its blood levels, in particular miR206. In
being followed up based on the com- addition, we have developed diagnos-
bined use of biochemical markers and tic algorithms that allow us to advance
genetic data.
in the identification of cognitively heal-
thy individuals, but with a higher risk of
developing cognitive impairment and
• MicroRNAs and lipid metabolism AD in the future. The results of the pro-
markers as potential links ject have led to numerous publications
between vascular dysfunction in international scientific journals and
and Alzheimer’s physiopathology have also been presented at various
national and international conferences.
This project, funded by MINECO (RE- Finally, two patents directly related to
TOS call for projects) and which has the results of the project have been
had Drs. Miguel Medina and Miguel registered, one of which has been
Calero as Principal Investigators, en- licensed to a Spanish biotechnology
ded on December 31, 2020. During this company.
period, the possible role of miRNAs
and lipid metabolism markers as pos-
sible links between peripheral vascular
dysfunction and the pathophysiology
of AD has been explored, having iden-
